Definition of pyrrolizidine alkaloid in English:

pyrrolizidine alkaloid


  • Any of a large class of toxic alkaloids with a structure based on pyrrolizidine, which occur widely in plants and can cause liver damage in humans and livestock if ingested.

    The alkaloids occur chiefly in the genera Senecio, Crotalaria, and Heliotropium.


1950s; earliest use found in Journal of the Chemical Society.