Definition of pythoness in English:

pythoness

Pronunciation /ˈpīTHənes/ /ˈpaɪθənɛs/

noun

archaic
  • A female soothsayer or conjuror of spirits.

    • ‘An elevated term for a witch was pythoness, which came to us in medieval times from medical Latin via French.’
    witch, sorceress, magician, fairy, fairy godmother

Origin

Late Middle English from Old French phitonise, from an alteration of late Latin pythonissa, based on Greek puthōn ‘soothsaying demon’. Compare with Pythia.