Definition of Pythonissa in English:

Pythonissa

Pronunciation /ˌpʌɪθəˈnɪsə/ /ˌpɪθəˈnɪsə/

noun

rare
  • Pythoness.

    Frequently treated as the proper name of the witch of Endor (1 Samuel 28:7).

Origin

Late Middle English; earliest use found in Geoffrey Chaucer (c1340–1400), poet and administrator. From post-classical Latin pythonissa (Vulgate), phitonissa woman with powers of divination from python-, pytho + classical Latin -issa.