Definition of scleroderma in English:



  • A chronic hardening and contraction of the skin and connective tissue, either locally or throughout the body.

    ‘Diseases as disparate as scleroderma, cystic fibrosis, kyphoscoliosis, sleep apnea, and sickle cell disease were found to have shared consequences in the pulmonary circulation.’
    • ‘People with this disorder have signs and symptoms of three diseases - lupus, scleroderma and polymyositis.’
    • ‘Rheumatic diseases such as rheumatoid arthritis, lupus, dermatomyositis, and scleroderma are thought to be autoimmune diseases.’
    • ‘Avoid face-lifts if you have lupus or scleroderma - autoimmune diseases - which affect your face.’
    • ‘She died on June 8, 2004, after a long and painful battle against scleroderma, a chronic disease of the immune system, connective tissue and blood vessels.’



/ˌsklerəˈdərmə/ /ˌsklɛrəˈdərmə/