Definition of verapamil in English:


Pronunciation /vəˈrapəməl/ /vəˈræpəməl/


  • A synthetic compound which acts as a calcium antagonist and is used to treat angina pectoris and cardiac arrhythmias.

    ‘The patient was treated with broad-spectrum antibiotics, verapamil and digoxin, and oxygen, and anticoagulation was adjusted.’
    • ‘If the fibrillation continues, the response of the ventricle can be slowed by beta blockers, verapamil or digitalis.’
    • ‘Her 54-year-old husband had hypertension treated with sustained-release verapamil.’
    • ‘Several blood pressure medications, including verapamil, but not Zestril, are also affected by grapefruit.’
    • ‘I take the blood pressure medicine, verapamil, at bedtime.’


1960s from v(al)er(onitr)il(e)(from valeric acid+ nitrile), with the insertion of -apam- (of unknown origin).