Basic Guidelines For English Spellings
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British English words that are spelled with the double vowels ae or oe are just spelled with an e in American English:
British | US |
leukaemia | leukemia |
manoeuvre | maneuver |
oestrogen | estrogen |
paediatric | pediatric |
Note that in American English, certain terms, such as archaeology, retain the ae spelling as standard, although the spelling with just the e (e.g., archeology) is usually acceptable as well.