SYNONYMS
fail, founder, be unsuccessful, not succeed, lack success, fall through, fall flat, break down, abort, miscarry, be defeated, suffer defeat, be in vain, be frustrated, collapse, misfire, backfire, not come up to scratch, meet with disaster, come to grief, come to nothing, miss the mark, run aground, go wrong, go awry, go astray
informal flop, fizzle out, come a cropper, bite the dust, blow up in someone's face, go down like a lead balloon
SYNONYMS
ruin, wreck, destroy, devastate, wreak havoc on, reduce to nothing, blight, smash, shatter, dash, torpedo, scotch, make a mess of, mess up
sabotage, poison
cancel out, neutralize, negate, render ineffective, make of no use or value
informal louse up, screw up, foul up, put the kibosh on, banjax, do for, blow a hole in, nix, queer
British informal scupper, cock up, dish, muller
Australian informal euchre, cruel
vulgar slang fuck up