Synonyms of of course in English:

of course

See US English definition of of course

See UK English definition of of course

See Spanish definition of claro


1‘there are, of course, exceptions to the rule’

naturally, as might be expected, as one would expect, as you would expect, needless to say, not unexpectedly, certainly, to be sure, as was anticipated, as a matter of course
obviously, clearly, it goes without saying
informal natch

2‘‘Have you got a minute?’ ‘Of course.’’

yes, certainly, definitely, absolutely, by all means, with pleasure
informal sure thing